Wirtz, a 22-year-old German international, is set to sign a record-breaking transfer deal with Liverpool, worth £116 million.
As a result, Leverkusen is searching for a new player to fill the gap left by Wirtz.
One potential replacement is Justin Kluivert, a 26-year-old forward from Bournemouth.
Ten Hag is said to be a strong supporter of Kluivert, believing that he has the right qualities to succeed in the team.
Another player who could join Leverkusen is Johan Bakayoko, a talented winger from PSV Eindhoven.